Searchable abstracts of presentations at key conferences in endocrinology

ea0022p154 | Cardiovascular endocrinology and lipid metabolism | ECE2010

Increased plasma resistin concentrations are associated with atherogenic small, dense low-density lipoproteins in patients with type-2 diabetes

Rizzo Manfredi , Amann-Vesti Beatrice , Zwimpfer Cornelia , Spinas Giatgen , Berneis Kaspar

Background: Resistin was originally proposed in animal models as a link between obesity and insulin resistance, but later studies in humans have shown a divergent role. Yet, resistin seems to be involved in the development of atherosclerosis in humans by promoting the formation of foam cells; further, its expression is induced by oxidized low-density lipoproteins (LDL) in human macrophages.Methods: We assessed the relationships between resistin and marke...